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A physician-supervised protocol that takes muscle preservation seriously addresses it through three non-negotiable pillars: Protein : approximately 1 g per pound of lean body mass daily, maintained consistently even when appetite is significantly suppressed Branched-chain amino acids : leucine in particular directly suppresses catabolism signalling at the source rather than just providing substrate

A person can have arterial stiffness without extensive plaque, plaque without obvious symptoms, or both processes at the same time

The rationale is that smaller individual doses may reduce GI side effects while maintaining the same total weekly exposure

Notwithstanding the impressive results that have been published to date, there is still a requirement for successful human trials to be completed prior to clinical translation