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A lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using systems toxicology assessment

Types of smoking Smoking cannabis Smoking cannabis (for example, smoking a joint) is the most harmful way of using cannabis because it directly affects your lungs

The descriptive analyses were further stratified for HICs (n=39) and LMICs (n=51)

It is suggested that induction of iNOS in response to ROS causes peroxynitrite-mediated damage to OPA1, sequentially leading to mitochondrial fragmentation, cytochrome c release and subsequent apoptosis (Park et al