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Scientists discovered the link between smoking and cancer back in the 1940s, but it's only been in more recent history that experts have understood the reason behind this cause and effect

Why Withdrawal Happens at All Nicotine is a highly addictive alkaloid that binds to nicotinic acetylcholine receptors (nAChRs) in the brain, triggering the release of dopamine the neurotransmitter associated with reward and pleasure [1]

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Common Nicotine Side Effects Include: Mouth sores Irritation in the oral cavity Blisters in the mouth Nausea Vomiting Sore throat Aside from the above symptoms, there are some side effects of nicotine that less commonly affect people but are even more worrisome