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Description

Nrf2 in cancers: a double-edged sword

Arrest of cell cycle entry by FZR-1 and LIN-35 Rb To examine cooperation between fzr-1 and lin-35 in cell cycle arrest, we tested how inactivation of these genes affects expression of mcm-4 S phase reporter constructs

In some cases, vacuolar peptidases may cleave the glutamate and glycine of the original glutathione molecule, leaving the cysteinyl conjugate (cysteine-X) which may need further processing in Phase III reactions, such as incorporation into cell wall material