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Similarly, excessive level of HBO1 mRNA in GC tissues and its negative correlation with GC patient survival indicated that HBO1 might act as a potential biomarker to predict patient prognosis [30]

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In the years 2022 and 2023, it was the 31st most prescribed drug with more than 18 million prescriptions and more than 4 million patients in the United States alone ( Thus, these compounds are commonly consumed by millions of individuals (Karatoprak, 2022

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