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Among high school students, smokeless tobacco use is highest among American Indian or Alaska Natives (9.2%), followed by whites (5.7%), Native Hawaiian or Pacific Islanders (5.3%), Hispanics (2.2%), blacks (0.9%), and Asians (0.7%)

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THC, CBD, and Throat Irritation THC and CBD themselves are not typically irritating, but the way they are delivered in vape form can contribute to discomfort

Nicotine, the addictive constituent of tobacco, meets these criteria because a typical withdrawal syndrome occurs after smoking cessation, tolerance to its use develops, and most importantly, use persists after developing symptoms attributable to the substance and in the face of its known harm