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44 Recent research highlights that sepsis, a condition that can be described as a systemic inflammatory response, is exacerbated in the absence of uteroglobin, and administration of this protein protected newborn rats with sepsis by blocking mitogen-activated protein kinase (MAPK) and extracellular signal-regulated kinase (ERK) signaling pathways

Smoking during pregnancy further increases the risk of spontaneous abortion and ectopic pregnancy

Moreover, CH patients might be biologically more vulnerable to compulsive pursuit of legal and illegal substances for a partial overlap/sharing of pathways which mediate addiction and are involved in the pathophysiology of CH