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doi: 10.1093/bib/bbab121 271

Probably yes

However, it has not been investigated whether the angiogenesis-promoting effect of SLC7A11 depends on or is independent of its downstream GSH/GPX4 pathway

Cuproptosis can modulate the expression of key genes involved in ferroptosis regulation, such as glutathione peroxidase 4 (GPX4), by eliminating phospholipid hydroperoxides [123, 124] and acylcoenzyme A synthetase long-chain family member 4 (ACSL4) [125], thereby regulating the sensitivity of cells to ferroptosis inducers