Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4) tamra Product Name Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4) Synonyms CAS

Product Name Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C50H82N8O19 Molecular Weight 1099

417 SMILES OC(=O)CCOCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

trisulfo CAS Number: N/A Molecular Formula: C35H46N6O10S3 Molecular Weight: 806

Eragidomide (CC-90009) is a cereblon (CRBN) E3 ligase modulator

Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4) tamra Product Name Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4) Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX