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Archived from the original on 26 March 2018

[60] suggested that there is a growing epidemic of cigarette smoking among female adolescents in LMICs, which might have contributed to the reduced sex-related differences in the burden of current smoking among adolescents in the lower and upper-middle-income countries as observed in the present study

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Ultimately, the advancement of NAMs will require engagement from both sides to ensure a mutual understanding that the proposed NAMs are providing information in the context of the current paradigm for regulatory risk assessments or explaining how the NAMs may be incorporated to inform an alternative approach for assessment