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The administration of curcumin remarkably enhances TGF- expression to suppress inflammation and progression in experimental encephalomyelitis (EAE) model of MS (Esmaeilzadeh et al., 2019)

257 peptides, derived from 142 proteins were significantly associated with sex, including CD99-derived cell adhesion peptides, which were enriched in males, a finding reliably observed across human brain and other tissue types 39,40

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Researchers started describing it as a genome reset, because the pattern in aged cells shifted back toward what youd expect from younger tissue (PMID: 25815981)