Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB dbco-maleimide 438 SMILES OCCCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC)

438 SMILES OCCCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

S)-AHPC-acetamido-O-PEG3-C1-acid Synonyms CAS Number 2360516-50-1 Related CAS Molecular Formula C32H46N4O10S Molecular Weight 678

and Escherichia coli dihydrofolate reductase (eDHFR)

At neutral pH

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB dbco-maleimide 438 SMILES OCCCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine