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The STEP 1 trial, published in the New England Journal of Medicine, demonstrated 14.9 percent mean body weight reduction with the 2.4mg weekly dose over 68 weeks, compared to just 2.4 percent with placebo

Some patients report: Rare: Allergic reactions or systemic effects have not been well-documented in available clinical data

For example, you might have a test 7 to 10 days after starting and another after about eight weeks

In those situations, professionalgrade supplements or B12 injections are often recommended to prevent deficiency. When to Consider Vitamin B12 Injections You may be a good candidate for vitamin B12 injections if you have a confirmed deficiency, ongoing fatigue, known absorption problems, or dietary patterns that make it hard to get enough B12 from food alone