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Government Money Market Fund Academy Class Janus Henderson Global Bond Fund - A Shares Janus Henderson Global Bond Fund - C Shares Janus Henderson Global Bond Fund - D Shares Janus Henderson Global Bond Fund - I Shares Janus Henderson Global Bond Fund - S Shares JPMorgan Government Bond Fund R2 Janus Henderson Global Allocation Fund - Growth - A Shares Janus Henderson Global Allocation Fund - Growth - C Shares JPMorgan Income Fund - C Janus Henderson Global Allocation Fund - Growth - I Shares Janus Henderson Global Allocation Fund - Growth - S Shares JPMorgan California Municipal Money Market Fund Institutional Class Janus Henderson Global Income Managed Volatility Fund - A Shares Janus Henderson Global Income Managed Volatility Fund - C Shares Janus Henderson Global Income Managed Volatility Fund - D Shares Janus Henderson Global Income Managed Volatility Fund - I Shares Janus Henderson Global Income Managed Volatility Fund - S Shares John Hancock Funds II Global Equity Fund Class C John Hancock Funds II Global Equity Fund Class I John Hancock Funds II Global Equity Fund Class R6 John Hancock Funds II Global Equity Fund Class R2 John Hancock Funds II Global Equity Fund Class R4 Janus Henderson Global Income Managed Volatility Fund N Shares John Hancock Funds II Multimanager 2060 Lifetime Portfolio Class R5 JPMorgan Income Fund - A Janus Henderson Growth and Income Fund - C Shares John Hancock Government Income Fund Class I Janus Henderson Growth and Income Fund - I Shares JPMorgan Intrepid Growth R5 JPMorgan Intrepid Growth Fund - R6 Janus Henderson Global Bond Fund - N Shares Janus Henderson Global Technology and Innovation Portfolio Institutional Shares JPMorgan Small Cap Growth Fund - R4 Janus Henderson Triton Fund - A Shares Janus Henderson Triton Fund - C Shares Janus Henderson Triton Fund - S Shares Janus Henderson Triton Fund - N Shares Janus Henderson Triton Fund - R Shares JPMorgan US Government Money Market Fd - Investor JPMorgan New York Municipal Money Market Fund Institutional Class Jensen Global Quality Growth Fund Class I Jensen Global Quality Growth Fund Class J Jensen Global Quality Growth Fund Class Y Janus Henderson Enterprise Fund - C Shares JPMorgan Small Cap Core Fund - R4 JPMorgan Growth Advantage Fund - R2 JPMorgan Small Cap Growth Fund - R3 JAG Large Cap Growth Fund Class R John Hancock Funds III Global Shareholder Fd Cl R6 Janus Henderson Enterprise Fund - S Shares JPMorgan Growth and Income Fund - R4 JPMorgan Small Cap Growth Fund R6 John Hancock Funds III Global Shareholder Yield Fd Cl R2 JPMorgan Small Cap Growth Fund-R5 John Hancock Funds II Multimanager 2060 Lifetime Portfolio Class R3 JPMorgan Growth Advantage Fund-R3 JPMorgan Growth Advantage Fund-R4 Janus Henderson Global Value Fund - T Shares JPMorgan Growth Advantage Fund R5 JPMorgan Growth Advantage Fund R6 Janus Henderson Government Money Market Fund - D Shares John Hancock Fds III John Hancock Fds III John Hancock Fds III John Hancock Fds III JHF II Multi-Asset Absolute Return Fund Class A JHF II Multi-Asset Absolute Return Fund Class C JHF II Multi-Asset Absolute Return Fund Class I John Hancock Freedom 529 Portfolio 2037-2040 Class F John Hancock Freedom 529 Portfolio 2037-2040 Class A JHF II Multi-Asset Absolute Return Fund Class R2 JHF II Multi-Asset Absolute Return Fund Class R6 Money Market Portfolio A John Hancock Bond Class B JHVIT Bond Trust - Series II Blue Chip Growth Portfolio F John Hancock Bond Fund Class I John Hancock Variable Insurance Trust Lifestyle Balanced Portfolio Series 1 John Hancock Bond Fd Cl R6 Janus Henderson Global Bond Fund - T Shares John Hancock Bond Fund Cl C John Hancock Funds II Absolute Return Currency Fund Class R2 John Hancock Variable Insurance Trust Lifestyle Conservative Portfolio Series 1 John Hancock Funds II Capital Appreciation Fund NAV Class John Hancock Freedom 529 Enrollment Portfolio Class F Money Market Portfolio C2 Portfolio 2029-2032 F John Hancock Freedom 529 Equity Portfolio Class A John Hancock Freedom 529 Equity Portfolio Class C2 John Hancock Funds II Equity Income Fund Class A John Hancock Funds II Emerging Markets Debt Fund Class R2 Equity Portfolio F JPMorgan Hedged Equity Fund I Class John Hancock Funds II Equity Income Fund Class C John Hancock Freedom 529 Fixed Income Portfolio Class A John Hancock Freedom 529 Fixed Income Portfolio Class C2 John Hancock Income Fund Class A Fixed Income Portfolio F Money Market Portfolio F John Hancock Funds II Global Equity Fund Class A John Hancock Government Income Fund Class A John Hancock Variable Insurance Trust Lifestyle Growth Portfolio Series 1 John Hancock High Yield Fund Class A John Hancock Funds III International Growth Fund Class R2 John Hancock Funds II Multi-Index 2060 Lifetime Portfolio Class R4 Equity Income Portfolio F John Hancock ESG Large Cap Core Fund Class A John Hancock ESG Large Cap Core Fund Class C John Hancock ESG Large Cap Core Fund Class I John Hancock ESG Large Cap Core Fund Class R6 John Hancock ESG All Cap Core Fund Class A John Hancock ESG All Cap Core Fund Class C John Hancock ESG All Cap Core Fund Class I John Hancock ESG All Cap Core Fund Class R6 John Hancock Funds II Multimanager Lifestyle Balanced Portfolio Class 5 John Hancock Funds II Multimanager Lifestyle Growth Portfolio Class 5 John Hancock Funds II Multimanager Lifestyle Moderate Portfolio Class 5 John Hancock Freedom 529 Portfolio 2037-2040 Class C2 John Hancock Fundamental Large Cap Core Fund Class C Mid-Cap Value Portfolio F Multimanager Lifestyle Growth 529 F Multimanager Lifestyle Moderate 529 F Multimanager Lifestyle Balanced 529 F John Hancock Variable Insurance Trust Lifestyle Moderate Portfolio Series 1 John Hancock Money Market Fund Class A John Hancock Bond Fund Class A New Horizons Portfolio F American Mutual Portfolio F John Hancock Var Ins Trust Money Market Tr Series I Portfolio 2025-2028 F JPMorgan Hedged Equity Fund - A JPMorgan Hedged Equity Fund - C JPMorgan Hedged Equity Fund - R5 JPMorgan Hedged Equity Fund - R6 John Hancock Bond Fd Cl R2 John Hancock Funds II Multimanager 2040 Lifetime Portfolio Class I John Hancock Funds II Multimanager 2015 Lifetime Portfolio Class I John Hancock Funds II Multimanager 2030 Lifetime Portfolio Class I John Hancock Funds II Multimanager 2010 Lifetime Portfolio Class I John Hancock Funds II Multimanager 2035 Lifetime Portfolio Class I John Hancock Funds II Multimanager 2025 Lifetime Portfolio Class I John Hancock Funds II Multimanager 2045 Lifetime Portfolio Class I John Hancock Funds II Multimanager 2050 Lifetime Portfolio Class I John Hancock Funds II Multimanager 2055 Lifetime Portfolio Class I John Hancock Funds II Multimanager 2020 Lifetime Portfolio Class I John Hancock Freedom 529 Short-Term Bond Portfolio Class A John Hancock Freedom 529 Short-Term Bond Portfolio Class C2 John Hancock Funds III U.S

Hepatothera from Klaire Labs is a natural dietary supplement that may support liver detoxification