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Domp Farmaceutici S.p.A NCT02187991

Numerous studies have demonstrated the diverse functions of mutant SOD1 using transgenic mice that express the protein

In recent decades, calcium channel blockers and modulators of mitochondrial dynamics, such as mitochondrial division inhibitor 1 (Mdivi-1) and the mitochondrial fusion promoter M1, have demonstrated cardioprotective and neuroprotective properties in various experimental models [129, 135, 136]