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It is likely that oxidative stress (OS) plays a role in the development and course of T2D

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BMC Genomics 11:73 Ji W, Zhu Y, Li Y, Yang L, Zhao X, Cai H, Bai X (2010) Over-expression of a glutathione S-transferase gene, GsGST, from wild soybean (Glycine soja) enhances drought and salt tolerance in transgenic tobacco

A well known observation in the art relates to the fact that GPCR receptors which are expressed inHEK293 cells have been shown to be functionally coupleleading to subsequent activation of phospoholipase C (PLC) and calcium mobilization, and/or cAMP stimuation or inhibition