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Table 27 Chemical purity (%) of cagrilintide in cagrilintide and semaglutide coformulations formulated with hydroxypropyl cyclodextrins of varying type Concluding Remarks The results presented in table 26 show that in co-formulation 24 (HP-G-CD), high numbers of sub-visible particles were observed already at time zero, which preclude the use of HP-G-CD to co-formulate cagrilintide and semaglutide

On the other hand, continued effort to improve efficacy, tolerability, and minimize side effects could allow drugmakers to justify higher prices for newer generations of these drugs

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