Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE exatecan 388 Purity (HPLC) >= 95%

388 Purity (HPLC) >= 95% Solubility DMSO

Rational discovery of molecular glue degraders via scalable chemical profiling

or other functional group—researchers can selectively label and study proteins in their native cellular environment

Solubility – reagent easily dissolve in water-miscible solvents for subsequent dilution into aqueous reaction mixtures

Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE exatecan 388 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate