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The mass spectroscopy was used for the identification of Jub B in the brain, and they revealed that significant amount of Jub B was present in the brain, it means that it can easily cross the BBB which is one the main barrier in the development of drugs against neurological disorders

The role of CAR in lipid metabolism remains controversial and may depend on the specific model and CAR agonist used, making it difficult to speculate on how CAR activation might affect lipid metabolism in sepsis (69, 82, 92, 93)

doi: 10.1128/iai.65.1.219-226.1997 135 ShenJLaiDHWilsonRAChenYFWangLFYuZLet al

Vial duration A 10 mg vial lasts ~5 weeks at 2 mg/week, ~2 weeks at 5 mg/week, and ~1 week at the upper 812 mg titration window