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Oxidative DNA damage estimated by urinary 8-Hydroxy-2' Deoxyguanosine (8-OHdG) and 8-Oxoguanine DNA Glycosylase (OGG1) in cigarette and non-cigarette smokers in South West Nigeria

And among these substances, there is a particularly prominent one, nicotine, which apart from being carcinogenic and able to cause immediate toxic effects (rise in cardiac frequency and blood pressure, and even acute intoxication syndromes), is all by itself responsible for cigarette dependency and the difficulty to quit smoking