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& Snyder, L

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The MTHFR polymorphisms are associated with an up to 70% decline in enzymatic activity, impairing methylation processes in the cell and resulting in elevations in homocysteine

Methods: We used the WHO International Standard to evaluate repeatability and reproducibility, and samples from our collection, with diverse genotypes and viral loads (VL), to assess sensitivity (lower limit of detection LLOD and quantification LLOQ) and specificity