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Class averages representing projections in different orientations selected from the initial 2D classification were used as templates for automatic particle picking from the full datasets

Results clearly showed that the c-met-binding of LASSS-treated HGF ( blue bars 4 ) was more than double that of the control level of HGF ( gray bars 3 , with the wash-out step)

Mitochondrial ablation in senescent cells suppressed CCF formation and activates p53, suggesting that mitochondria-dependent formation of H2A.X and CCF dampens nuclear DNA damage signaling and p53 activity in the tissue (Miller et al., 2025)