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Specially, we are finalizing at 180.50, the removal of the estimated allowed amount, disclosure of the 10th percentile, median, 90th percentile allowed amounts and the count of allowed amounts, the attestation requirements, and the requirement to encode hospital NPIs effective January 1, 2026

High-dose or prolonged pyridoxine supplementation can also lead to alterations in other nutrient levels, for example, extended use of large doses has been associated with reduced serum folate concentrations in some reports, which suggests a need to monitor nutritional balance during long-term therapy

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