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Description

Evidence Boundary Most studied route in the Phase 2 program, but the OPTIONS trial missed its primary weight-loss endpoint and development was terminated in 2007

MOTS-c prevents diet-induced obesity and insulin resistance by improving glucose utilization and maintaining adipose homeostasis [5]

Field 2: Origin 5-Amino-1MQ : synthetic, full stop

Regulatory Note: AOD 9604 has been designated Generally Recognized As Safe (GRAS) for certain food-related applications by an expert panel, but is not FDA-approved for medical or dietary use