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89 Role of ferroptosis in human diseases Increasing evidence has shown that ferroptosis has an important role in many biological and pathological processes and is involved in the onset and progression of multiple human diseases (Fig

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Substances that are absorbed through the buccal route go directly into the systemic circulation and this eliminates disadvantages imposed by oral intake, such as the decreased ability of GSH to pass through the gastrointestinal tract as an intact molecule

When iron limitation in cells, ferritin is mobilized to the lysosome via NCOA4 to degrade and liberate the stored iron