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This suggests that Oldenlandia diffusa could be an intriguing target for future therapeutic interventions

Important limitations include: Most evidence derives from preclinical or observational studies No randomized controlled trials specifically evaluate tirzepatide for autoimmune disease Mechanisms remain incompletely understood Clinical translation of anti-inflammatory effects is uncertain There is currently no established clinical evidence that tirzepatide effectively treats autoimmune diseases

Preclinical acute toxicity is low, with reported rodent LD50 values well above any human-equivalent research dose