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PMID:21453958 Zhang B, Weng Z, Sismanopoulos N, Asadi S, Therianou A, Alysandratos KD, Angelidou A, Shirihai O, Theoharides TC: Mitochondria Distinguish Granule-Stored from de novo Synthesized Tumor Necrosis Factor Secretion in Human Mast Cells

Together, the data indicates that proper mitochondrial function and dynamics are also essential for establishing the epigenetic landscape required for successful implantation and early development (Fig