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10.1158/1535-7163.MCT-15-0017 Mol Cancer Ther 32 LiuT.MaX.OuyangT.ChenH.XiaoY.HuangY.et al (2019)

A 2008 study in British Journal of Clinical Pharmacology found that oral L-citrulline increased plasma L-arginine levels more effectively than L-arginine itself

PGRMC1 ablation protects from energy-starved heart failure by promoting fatty acid/pyruvate oxidation

As a result, intestinal tumors from Apc +/Min /Stard7 IEC mice are expected to be less sensitive to serine deprivation, as previously described for K-Ras-driven intestinal tumors (Maddocks et al, 2017)