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With regard to measure reporting, we estimate the removal of this measure will decrease burden for voluntary reporting for the CY 2025 reporting period by 383 hours (4,590 ASCs 50 percent of ASCs 0.167 hours per ASC) at a savings of $21,088 (383 hours $55.06/hour) and 765 hours annually (0.167 hours 4,590 ASCs) at a savings of $42,121 (765 hours $55.06/hour) for mandatory reporting beginning with the CY 2026 reporting period

Its safety and efficacy in humans or animals have not been established

The role of these proteins in promoting focal adhesion turnover is further supported by the findings that the inhibition of CLASPs or LL5 using RNAi technology or the pharmacological inhibition of MMP activity prevents the turnover or focal adhesions in migrating keratinocytes [74]

Biochemistry (2005) 44:730514