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Rapid deletion of rearranged T cell antigen receptor (TCR) V-J segment by secondary rearrangement in the thymus: role of continuous rearrangement of TCR chain gene and positive selection in the T cell repertoire formation

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There is a significant increase in the incidence of allergic and autoimmune diseases, such as asthma, atopic dermatitis, allergic rhinitis, chronic sinusitis, food allergies, celiac disease and inflammatory bowel disease

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