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This phenotypic transformation is likely mediated by the miRNA-mRNA network within exosomes, with the miR-23a-3p/PTEN/PI3K/AKT axis playing a pivotal role

These coordinated responses promote TFEB nuclear translocation, enhance lysosomal and autophagic gene expression more effectively than rapamycin and attenuate phosphorylated tau, total tau and p62 accumulation, highlighting zincs therapeutic potential in restoring lysosomal proteolysis and autophagy 103,167

The perimeter of each square wound was traced onto a sterile piece of clear acetate film by an examiner wearing a 2.5x loupe

Vitamin C status in patients with acute pancreatitis