nf1 glutathione loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma neurofibromotosis glutathione Cutaneous neurofibromas in

5% (w/v) milk (non-fat milk powder in TBST) was used to block nonspecific binding sites at room temperature for 2 h

In farmed animals, the antioxidant system, which encompasses enzymes (e.g., SOD, CAT, GPx) and low-molecular-weight compounds (e.g., vitamins C/E, glutathione [GSH]), collectively neutralizes reactive oxygen species (ROS) to maintain cellular homeostasis and prevent oxidative tissue damage

However, because oxidants react too quickly with membrane lipids, proteins, and nucleic acids to be effectively removed by exogenous small molecules, preventing the production of ROS is the focus of the first line of defense

Bibbiani F, Oh JD, Petzer JP, Castagnoli N Jr, Chen JF, Schwarzschild MA, Chase TN (2003) A2A antagonist prevents dopamine agonist-induced motor complications in animal models of Parkinsons disease