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Jacquelot N, Xiong L, Cao WHJ, Huang Q, Yu H, Sayad A, et al

Given the title of the paper by Foyer and Halliwell (1976), it is intriguing that notable exceptions to this redundancy are glutathione synthesis, ascorbate synthesis, and chloroplastic GR activity (Cairns et al

Nuclear factor erythroid-2 related factor 2 (Nrf2) is an important transcription factor that regulates cellular oxidative stress, which binds to antioxidant response element sites and regulates antioxidant-mediated gene expression and induction ( Early studies have shown that heavy metal Cd promotes the release of iron in biomembrane and this free iron participates in Fenton-type reactions, thus generating ROS ( 0 site of cytochrome b of mitochondrial complex III, leading to the accumulation of semiubiquinone at the q 0 site, generating ROS and causing oxidative stress (Wang et al., 2004)