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Generation of Metabolic CRISPR-Cas9 Library Metabolism associated genes from previously published CRISPR-Cas9 screening libraries 19,48,92 and the Mammalian Metabolic Enzyme Database 93 were collated, converted into human gene equivalents (in the context of mouse genes as appropriate), and replicates removed

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Some of the common uses of peptides include: Medical Treatments Peptides are used in over 100 FDA-approved drugs to treat conditions such as: Diabetes (e.g., liraglutide, semaglutide) Osteoporosis (e.g., teriparatide) Chronic pain (e.g., ziconotide) HIV (e.g., enfuvirtide) Cancer (e.g., carfilzomib for multiple myeloma) Because peptides can be designed to interact with specific receptors in the body, they often have fewer side effects than traditional drugs