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Usage Instructions: Dosage: Mild Cases: One ampoule every three days

Third, although we focused exclusively on female patients in line with the epidemiology of lipedema, future studies should consider potential sex-specific differences and include appropriate controls for hormonal status, menopausal state, and body mass index (BMI)

The trial enrolled 281 participants across 42 research and healthcare centers in the United States, randomized to once-weekly subcutaneous retatrutide (0.5, 4, 8, or 12 mg), once-weekly subcutaneous dulaglutide 1.5 mg (active comparator), or placebo, over a 36-week treatment period