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Exogenous delivery of H 2 S in a form of S -propargyl-cysteine in a special liposomal formulation, which leads to the slow release of the active gasotransmitter, had cardioprotective and anti-fibrotic effects by inhibiting the TGF-1/SMAD signaling pathway [235]

In rodent tendon and ligament injury models, treated animals showed accelerated tenocyte proliferation and faster collagen-fiber organization versus controls

56 reported that intracellular reactive oxygen species and all amino acids, including glutamine, were increased in the NH 4 Cl-treated human astrocyte

Khouri, I, Kantarjian H, Talpaz M, Andreeff M , M-S L, Champlin R, Deisseroth AB