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Five factors were selected for the prediction model, including age, qualifying event, diabetes, stenosis degree and internal carotid artery stenosis

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While pineal melatonin regulates the circadian rhythms, extra pineal melatonin performs various functions beyond its primary role, which includes acting as an antioxidant, stimulating the production of endogenous antioxidant enzymes, scavenging free radicals, and playing a homeostatic role within mitochondria (ArandaMartnez et al

For instance, water retention has been seen in some cases of patients with GH excess