glutathione h202 H2O2 is metabolized to nontoxic products by peroxidase The supplement comes in acid GSSG Application

Li J, Liu H, Ramachandran S, Waypa GB, Yin JJ, Li CQ,

The loss of either of the glial L-glu transporters (EAAT1 and EAAT2) but not the neuronal transporter (EAAT3) resulted in large increases in extracellular L-glu concentrations in the striatum after 7 days as determined by microdialysis (EAAT2, 32-fold increase

Finally, translational implications remain speculative because most interventions targeting mitochondrial or inter-organellar functions have been tested in prophylactic or early-treatment settings in animals, with little evidence regarding their efficacy, safety, and feasibility in established, severe disease in humans

Determining the correct dosage, method of administration, and length of each treatment was a steep learning curve