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Serious skin problems: Symptoms include blisters, skin sores, skin peeling, or ulcers in the mouth, nose, throat, or genital area

Useful soft tissue endpoints include: muscle fibre organisation vascular response inflammatory marker panels collagen deposition fibroblast activity oxidative stress markers histology scoring cell migration These research areas overlap with tendon and ligament studies but focus more broadly on tissue integrity and repair-associated signalling

The vast majority of patients we see for B12 shots or B cocktails are those who are tired all the time and generally feel weak and run down

Lancet , 367 , 1605-1617