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An oligonucleotide is specifically hybridizable when binding of the oligonucleotide to the target interferes with the normal function of the target molecule to cause a loss of utility or expression therefrom, and there is a sufficient degree of complementarity to avoid non-specific binding of the oligonucleotide to non-target sequences under conditions in which specific binding is desired, i.e., under physiological conditions in the case of in vivo assays or therapeutic treatment, or, in the case of in vitro assays, under conditions in which the assays are conducted

The mitochondria-targeted antioxidant MitoQ inhibits memory loss, neuropathology, and extends lifespan in aged 3xTg-AD mice

Because of its defined amino acid structure and reproducible synthesis profile, it is often included in controlled laboratory research evaluating peptide behavior, formulation characteristics, and analytical peptide performance

6 Regulatory statusSelank (Russian trade name) is a registered intranasal anxiolytic in Russia/Ukraine only