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Furthermore, downregulation of nuclear factor E2-related factor 2 (Nrf2) leads to reduced GPX4 expression, thereby intensifying ferroptosis (Ni et al., 2020

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Bucillamine induces the intranuclear translocation of Nrf2 and thereby increases the expression of -glutamylcysteine synthetase (-GCS) and glutathione synthetase (GSS), which further induces intracellular antioxidant glutathione (GSH), heme oxygenase 1 (HO-1) and superoxide dismutase 2 (SOD2)

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10.1016/0092-8674(94)90345-x 21 DanksD

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Mi SciELO Servicios Personalizados Revista Articulo Indicadores Citado por SciELO Accesos Links relacionados Similares en SciELO Compartir Nutricin Hospitalaria versin On-line ISSN 1699-5198 versin impresa ISSN 0212-1611 Nutr

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