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Interleukin-6 expression in human multiple sclerosis lesions

56-58 Not only is 15d-PGJ2 a potent Nrf2 agonist, that markedly increases cellular antioxidants, but it also has potent anti-inflammatory properties related to its capacity to S -alkylate several key cysteine residues in proteins regulating inflammatory pathways including NFkB and PPAR

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SC: Data curation, Methodology, Writing original draft