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Methods: This analysis includes data from participants who have received at least 24 weeks ( 6 doses) of tobevibart 300 mg and elebsiran 200 mg subcutaneously every 4 weeks (Q4W) and are on nucleoside reverse transcriptase inhibitors in the ongoing MARCH, STRIVE, and THRIVE studies in participants with CHB (NCT04856085 and NCT05612581) and the SOLSTICE study in participants with CHD (NCT05461170)

2 and 3) through the modulation of multiple targets and pathways involved in the pathophysiology of these diseases