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All procedures followed institutional and national ethical guidelines, approved by the University of Oxfords Animal Welfare and Ethical Review Board (AWERB), and adhered to the Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines

With the rise of precision nanomedicine, HA-coated nanoparticles and hydrogels will continue to evolve as vehicles for targeted drug delivery, especially in oncology, where CD44 receptor-mediated targeting is showing consistent promise

10.1093/ehjci/jet132 [DOI] [PMC free article] [PubMed] [Google Scholar] Nascimento-Souza M

Because the half-life is about 5 days, with weekly dosing blood levels rise for the first 4 weeks before stabilizing