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Common plateau scenarios include: The circulation bottleneck: repair stalls because nutrient delivery is insufficient The remodeling bottleneck: pain improves but stability does not return The inflammation bottleneck: repair attempts are repeatedly interrupted by flare cycles The structure bottleneck: collagen forms but remains disorganized and weak GLOW is designed to support these simultaneously

Storage Guidelines and Safe Administration Proper handling of Epitalon is essential to ensure its potency: Storage : Keep the lyophilized (powdered) form in a cool, dark environment ideally refrigerated at 28C

TB-500, by contrast, works more systemically

Supplementary Figure S2A,B)