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However, retinal neovascularization is typically accompanied by hypoxia-induced oxidative damage

Cancer Cell 39 , 14791496.e18 (2021)

Studies have shown that tight junction integrity is regulated by cytokines TNF- and IFN-, and the IFN- can inhibit the expression of ZO and occludin to increase intestinal permeability (Scharl et al., 2009)