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The overproduction of reactive oxygen species (ROS) can directly damage cellular components (lipids, proteins, and nucleic acids), thereby exacerbating inflammation and tissue injury (Zhou et al., 2025

Drug interactions can occur at this point in the process as certain medications and herbal supplements including St

RPE cells in AMD were observed with decreased PINK1 mitophagy pathway, affecting mitophagy and increasing ROS, which induces epithelial-mesenchymal transition