Importantly, these phenotypes contrast with the non-inducible liver-specific Gclc KO mouse strain ( Gclc f/f Albumin-Cre), which develops liver failure and dies shortly after birth 30
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Finally, challenges and future directions regarding the investigation of ferroptosis are discussed
To interrogate this, we utilized an AAV-TBG-Cre viral delivery system, which produces liver-specific Cre expression and subsequent genetic deletion 49,50
