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The short of it is that fatigue and reduced athletic performance isnt driven so much by muscle glycogen depletion as it is, likely, from a central nervous system mechanism that can be hacked by just giving a tiny bit of carbs during very high intensity exercise to keep the blood supply from dropping the carb equivalent of ~1/2 tsp of honey per 20 min of intense exercise

According to a 2023 study[1] published in the journal, Dermatology Online , There are a number of reports on the onset of acute annular pustular psoriasis with the COVID-19 vaccine as well the development of pustular psoriasis in a patient with established plaque psoriasis following the administration of the vaccine It has been suggested that certain cutaneous COVID-19 vaccine reactions may represent unmasking of subclinical inflammatory dermatoses due to the immune boosting properties of the vaccine

And to do that, regardless of where the injury is, they'll do that in one particular site

Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study