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ThT aggregation studies show the PSM3 peptide inhibits aggregation by 90% at equimolar concentrations between PSM3 and S after 32 h

However, DOPAL can be detoxified by NAD(P) + -dependent aldehyde dehydrogenase (ALDH) or reduced by aldehyde/aldose reductase (ALR/AR) to form the inactive 3,4-dihydroxyphenylethanol, or further oxidized to non-toxic 3,4-dihydroxyphenylacetic acid where the aldehyde moiety is replaced by a carboxyl group [32]

For establishing the allograft and xenograft tumor models, 5 10 6 Hepa1-6 cells and 110 6 KYSE-150 cells were respectively injected into C57BL/6 J and BALB/c-nu mice at their left lower abdominal region